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What is Androgenetic Alopecia?

Androgenetic alopecia is an inherited type of hair loss that is common in men and women. Male pattern hair loss is caused by genetic predisposition and hormones and usually begins with thinning hair and receding hairline. Androgenetic alopecia, also known as ‘male pattern baldness’ in men, causes similar hair thinning in women.  In this article, we will provide detailed information about the causes, symptoms and treatment methods of androgenetic alopecia.

What is Male Pattern Baldness (Androgenetic Alopecia)?

Male pattern baldness, scientifically referred to as androgenetic alopecia, stands as the predominant form of hair loss observed in men.This condition is caused by genetic predisposition and male hormones called androgens. Androgenetic alopecia usually begins after puberty and becomes more pronounced with age. It is characterized by regression of the hairline and thinning of the hair on the crown in men. The hair follicles shrink over time and the hair strands become thinner and their growth phase is shortened, leading to easier hair loss. Since male pattern baldness is a hereditary trait, it is more common in individuals with a family history of similar hair loss.

What Causes Androgenetic Alopecia?

Factors Causing Male Pattern Baldness:

Age:

The likelihood of male pattern baldness increases with age. About 25% of men have the first signs of hair loss before the age of 21. By the age of 50, half experience hair loss and about 70% lose their hair as they age.

Hormones

Dihydrotestosterone (DHT) is a type of androgen. Androgens are a group of sex hormones that initiate puberty and physical maturation in humans. These hormones affect hair growth on the face, scalp, chest, armpits and genitals. Medical experts and researchers think that DHT may be linked to shrinking hair follicles.

Genetics:

Men receive one X chromosome from their mother and one Y chromosome from their father through genetic inheritance.The AR gene on the X chromosome determines how androgens are produced in the body. The sensitivity of the AR gene plays an important role in determining the risk of male pattern baldness.

Symptoms of Androgenetic Alopecia

Androgenetic alopecia is characterized by certain symptoms in both men and women. These symptoms are caused by genetic predisposition and hormones. The general symptoms of this condition, which can progress in different ways in men and women, are as follows:

  • Thinning and weakening of the hair
  • Expansion of hair loss areas
  • New hair grows thinner and shorter
  • Receding hairline (especially in men)

Symptoms of Androgenetic Alopecia in Men

In men, the symptoms of androgenetic alopecia are usually more pronounced and specific:

  • A circular hair loss is observed in the crown area.
  • The hairline recedes starting from the temples and hair loss occurs in these areas.
  • The hairline usually recedes in an “M” shape.
  • Hair loss at the crown and temples combines over time to form a “U” shaped appearance.
  • Male pattern baldness is usually noticed in the 30s, but can sometimes start in the late teens or early 20s.

Symptoms of Androgenetic Alopecia in Women

Symptoms of androgenetic alopecia in women may be more diffuse and less pronounced than in men:

  • Hair loss in women is more diffuse and homogeneous.
  • Thinning and thinning is particularly noticeable at the crown of the head.
  • In women, the hairline is usually preserved, but the hair density is reduced.
  • The hair parting is markedly widened and more scalp is visible.
  • In women, androgenetic alopecia usually becomes apparent in the postmenopausal period, i.e. in the 40s and 50s.

These symptoms are important for early diagnosis of androgenetic alopecia and for determining appropriate treatment methods. These symptoms in both men and women can be controlled with appropriate treatment and management.

How is Androgenetic Alopecia Diagnosed?

Androgenetic alopecia is usually diagnosed by clinical evaluation. The dermatologist or hair transplant specialist examines the patient’s hair loss pattern and evaluates the family history. On physical examination, the diagnosis can be made if miniaturized hair follicles and thinning are evident on the scalp. In addition, the condition of the hair follicles can be examined in more detail with imaging methods such as dermatoscopy. Rarely, blood tests or hair tests may be performed to rule out other causes of hair loss.

Androgenetic Alopecia Treatment

Treatment of androgenetic alopecia can involve a variety of methods and better results are often achieved with a combination of several treatment approaches. 

1. Drug Therapy:

Minoxidil: This topically applied medication can slow hair loss by prolonging the growth phase of the hair follicles and may promote hair regrowth in some people.

Finasteride: This oral medication may slow hair loss by lowering dihydrotestosterone (DHT) levels. It is used in men and is not usually recommended for women.

Dutasteride: works similarly to finasteride but is more potent and inhibits both type I and type II isoenzymes of DHT.

2. Hair Transplant 

Hair transplantation is one of the most common and effective treatments for androgenetic alopecia. This procedure involves removing hair follicles from the donor area (usually the back and sides of the head) and transplanting them into balding or sparse areas. Hair transplantation is usually performed under local anesthesia and can take a few hours to a day. Post-procedure care and recovery may vary depending on the transplant method and the person’s health condition.

3. Hair Laser

Hair Laser (Low Level Laser Therapy – LLLT) is a non-invasive treatment aimed at slowing hair loss and stimulating hair growth. By applying low levels of laser light to the hair follicles, LLLT increases cell metabolism, improves blood circulation and stimulates hair growth. Laser hair treatment is usually performed several times a week and does not cause any pain or discomfort. This treatment can also be used in combination with other hair loss treatments.

4. Exosome Hair Treatment

Exosome Hair Treatment is an innovative treatment method that has gained popularity in recent years. Exosomes are small vesicles that enable cell-to-cell communication and contain growth factors and proteins. This treatment involves injecting exosomes into the scalp, which stimulate hair follicle regeneration and hair growth. Exosomes are applied to the scalp by micro-needling or direct injection. Typically, this procedure is conducted using local anesthesia and is characterized by minimal invasiveness.Exosomes revitalize hair follicles, reduce hair loss and promote new hair growth. Recovery after treatment is usually fast and side effects are minimal.

5. Stem Cell Hair Treatment

Stem Cell Hair Therapy is a treatment that uses stem cells to stimulate hair follicle regeneration and new hair growth. This treatment offers promising results to stop hair loss and increase hair density. Stem cells are usually derived from a person’s own adipose tissue or bone marrow. These cells are isolated and multiplied in the laboratory and then injected into the scalp. The stem cells allow the hair follicles to be repaired and reactivated. This treatment reduces hair loss and increases hair density. The healing process is usually fast and natural-looking results are achieved.

Stem cell hair treatment is usually minimally invasive and performed under local anesthesia. This treatment is revolutionizing hair loss treatments and is expected to reach a wider audience with further research and development.

 

Androgenetic alopecia treatment offers many innovative and effective ways to stop hair loss and stimulate new hair growth. Methods such as hair transplantation, hair laser, exosome hair treatment and stem cell hair treatment offer personalized solutions, making it possible to achieve fuller and healthier hair. Esteworld hair specialists determine the most appropriate treatment method after a detailed evaluation since each individual’s hair loss condition and response to treatment is different. If you are dealing with significant hair loss, you can contact us for detailed information about hair transplantation and our treatments.

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What Causes Androgenetic Alopecia?

Androgenetic alopecia, often referred to as male or female pattern baldness, is mainly influenced by genetic and hormonal elements.. The condition is linked to androgens, particularly dihydrotestosterone (DHT), which affects hair follicles. DHT binds to receptors in the hair follicles, causing them to shrink over time. This process leads to a shorter hair growth cycle and gradually finer, shorter hair until growth stops entirely. The genetic predisposition to androgenetic alopecia can be inherited from either parent, making it a common hereditary condition.

Hair regrowth in androgenetic alopecia is possible but varies from person to person. Treatments like minoxidil (a topical solution) and finasteride (an oral medication) can slow hair loss and promote hair regrowth to some extent. Minoxidil works by stimulating hair follicles and increasing blood flow to the scalp, while finasteride reduces DHT levels. Additionally, advanced treatments like low-level laser therapy (LLLT), platelet-rich plasma (PRP) injections, and hair transplantation can also aid in hair regrowth. However, complete restoration of hair is challenging, and maintaining results often requires ongoing treatment.

Currently, there is no definitive cure for androgenetic alopecia. Treatments can effectively manage the condition by slowing hair loss and promoting partial regrowth, but they do not completely eradicate the underlying causes. Consistent use of medications like minoxidil and finasteride, along with advanced procedures such as hair transplants and PRP therapy, can significantly improve hair density and appearance. Research is ongoing, and future advancements may offer more permanent solutions, but as of now, managing the condition requires ongoing treatment.

Alopecia is a general term for hair loss from any part of the body, due to various causes. It includes conditions like alopecia areata (an autoimmune disorder causing patchy hair loss), telogen effluvium (temporary hair thinning due to stress or illness), and traction alopecia (hair loss from repeated strain or pulling).

Androgenetic alopecia, on the other hand, specifically refers to hair loss caused by genetic and hormonal factors, leading to a characteristic pattern of hair thinning. In men, it often results in a receding hairline and balding on the crown, while in women, it typically manifests as diffuse thinning over the entire scalp. Unlike other forms of alopecia, androgenetic alopecia is progressive and often requires long-term management.

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